Stock-based Activity (Details 1) - $ / shares	6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015
Options Outstanding
Options Outstanding, Outstanding at beginning of period	3,243,041
Options Granted	1,655,500	2,615,850
Options Exercised	0
Options Forfeited/cancelled/expired	(219,449)
Options Outstanding and expected to vest at end of period	4,679,092
Vested and exercisable at June 30, 2016	1,005,213
Weighted-Average Exercise Price
Weighted-Average Exercise Price, Outstanding at beginning of period	$ 2.36
Weighted-Average Exercise Price, Granted	.73
Weighted-Average Exercise Price, Exercised	0
Weighted-Average Exercise Price, Forfeited/cancelled/expired	2.30
Weighted-Average Exercise Price, Outstanding and expected to vest at end of period	1.90
Weighted-Average Exercise Price, Vested and exercisable at June 30, 2016	$ 2.54