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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Operating activities    
Net loss $ (4,404,770) $ (2,447,320)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 8,340 4,323
Stock-based compensation 1,533,888 82,772
Restricted stock issued for services 64,000 0
Change in fair value of warrants 0 (19,807)
Debt discount amortization 71,547 0
Increase (decrease) in operating assets and liabilities:    
Grant receivable 483,924 (155,195)
Other receivables 0 2,275
Prepaid expenses and other 69,650 44,474
Accounts payable (1,060,796) 753,184
Accrued clinical operations and site costs 81,949 22,847
Accrued compensation (98,927) 88,434
Other accrued expenses 339,565 200,483
Net cash used in operating activities (2,911,630) (1,423,530)
Investing activities    
Purchases of property and equipment (153,899) (28,867)
Net cash used in investing activities (153,899) (28,867)
Financing activities    
Cash received from bank loan, net of financing costs 4,610,324 0
Issuances of common stock, net of issuance costs 0 4,714,726
Net cash provided by financing activities 4,610,324 4,714,726
Net change in cash and cash equivalents 1,544,795 3,262,329
Cash and cash equivalents at beginning of period 4,084,085 1,477,143
Cash and cash equivalents at end of period 5,628,880 4,739,472
Supplemental disclosures of non-cash investing and financing information:    
Capital lease in connection with purchases of equipment 95,656 0
Purchase of equipment in accounts payable 109,471 0
Deemed dividend on beneficial conversion feature for preferred stock 0 17,852,921
Accretion of redemption value for Series A-1 and B preferred stock 0 93,234
Conversion of Series A-1 redeemable preferred stock into common stock 0 162,968
Conversion of Series C preferred stock to common stock 0 966
Conversion of Series B preferred stock to common stock 0 160,380
Exchange of Series A-1 preferred stock and warrants into common stock and Series D preferred stock 0 13,111,280
Exchange of Series B preferred stock and warrants into common stock and Series D preferred stock 0 10,451,784
Fair value of warrants issued $ 607,338 $ 0