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Collaboration Agreements (Details)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended 21 Months Ended
Sep. 07, 2016
USD ($)
shares
Oct. 31, 2016
USD ($)
program
Sep. 30, 2016
USD ($)
program
shares
Jan. 31, 2015
Jun. 30, 2003
USD ($)
Sep. 30, 2016
USD ($)
program
Jun. 30, 2016
USD ($)
Mar. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
payment
right
product
term
program
patient
Sep. 30, 2015
USD ($)
Sep. 30, 2016
USD ($)
program
Sep. 30, 2015
USD ($)
Dec. 31, 2015
USD ($)
payment
right
product
term
program
patient
Sep. 30, 2016
USD ($)
program
Sep. 06, 2016
$ / shares
Oct. 31, 2015
USD ($)
program
Dec. 31, 2012
USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Recognized royalty revenue           $ 1,817,000       $ 2,293,000 $ 5,403,000 $ 5,998,000          
Cost of royalty revenues           94,000       116,000 278,000 303,000          
Collaboration agreement, number of optional additional terms | term                 3       3        
Collaboration agreement, optional additional term                         1 year        
Option fees                         $ 7,500,000        
Number of payments | payment                 2       2        
Closing share price of common stock (in dollars per share) | $ / shares                             $ 1.76    
Curis Royalty | Credit agreement with BioPharma-II                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Principal loan amount to Curis Royalty given by BioPharma under credit agreement                                 $ 30,000,000
Interest rate on loan to Curis Royalty given by BioPharma under credit agreement                                 12.25%
Genentech, Inc.                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Amount received for specified clinical development and regulatory objectives     $ 59,000,000     59,000,000         59,000,000     $ 59,000,000      
Percentage of royalty rate decrease         2.00%       2.00%                
Recognized royalty revenue           1,800,000       2,300,000 5,400,000 6,000,000          
Cost of royalty revenues           $ 100,000       $ 100,000 $ 300,000 $ 300,000          
Percentage of royalties earned           5.00%       5.00% 5.00% 5.00%          
Genentech, Inc. | Drug development royalty                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Research and development revenue           $ 100,000       $ 100,000 $ 200,000 $ 200,000          
Research and development expenses           $ 100,000       $ 300,000 $ 400,000 $ 400,000          
Genentech, Inc. | Maximum                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Eligible to receive contingent cash payment for specified clinical development and regulatory objectives (up to)         $ 115,000,000                        
Percentage of royalty on net sales         7.50%                        
Genentech, Inc. | Minimum                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Percentage of royalty on net sales         5.00%                        
Aurigene                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Collaboration agreement, option exercisable period       90 days                          
Collaboration agreement, number of programs licensed | program     2     2     2   2   2 2   2  
Collaboration agreement payment                         $ 6,000,000        
Additional payments made under collaborative arrangements (up to)                               $ 2,000,000  
Research and development expenses           $ 18,000,000   $ 1,000,000 $ 1,000,000   $ 18,000,000            
Payments for research and development             $ 1,000,000 $ 1,000,000                  
Payment for preclinical program for potential further development                         $ 2,000,000        
Collaboration agreement, number of products required to commercialize (at least) | product                 1       1        
Collaboration agreement period                         2 years        
Collaboration agreement, rights granted to nominate global drug substance or drug product supplier | right                 1       1        
Payments made under collaboration arrangements                           $ 11,000,000      
Shares issued of common stock in exchange for waived payment (in shares) | shares 10,208,333   10,208,333                            
Waived payment of milestone and other payments (up to) $ 24,500,000   $ 24,500,000                            
Value of common stock issued 18,000,000                                
Aurigene | Subsequent event                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Collaboration agreement, number of programs licensed | program   3                              
Payment for license and designation as the development candidate   $ 1,500,000                              
Aurigene | PD1/VISTA programs                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Collaboration agreement payment                         $ 3,000,000        
Collaboration agreement expenses, option exercise                         3,000,000        
Collaboration agreement expenses, acceptance of IND filing           3,000,000             3,000,000        
Collaboration agreement expenses, dosing of fifth patient                         4,000,000        
Aurigene | IRAK4 programs                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Collaboration agreement payment                         3,000,000        
Collaboration agreement expenses, option exercise                         3,000,000        
Collaboration agreement expenses, acceptance of IND filing                         3,000,000        
Collaboration agreement expenses, dosing of fifth patient                         4,000,000        
Aurigene | Programs three and four                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Agreement to provide additional funding, if options are exercised (up to) 2,000,000                                
Aurigene | Program three                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Collaboration agreement expenses, option exercise                         3,000,000        
Collaboration agreement expenses, acceptance of IND filing                         2,500,000        
Payments made under collaboration arrangements                           2,000,000      
Collaboration agreement expenses, program selection fee                         2,000,000        
Aurigene | Program four                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Collaboration agreement expenses, option exercise                         3,000,000        
Collaboration agreement expenses, acceptance of IND filing                         2,500,000        
Collaboration agreement expenses, program selection fee                         2,000,000        
Aurigene | Program thereafter                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Additional payments made under collaborative arrangements (up to)     $ 0     $ 0         $ 0     $ 0      
Collaboration agreement, fees (up to)                         $ 53,000,000        
Aurigene | Extended exclusivity, IRAK4 program                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Waived payment of milestone and other payments (up to) 1,000,000                                
Aurigene | Acceptance of IND filing, IRAK4 program                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Waived payment of milestone and other payments (up to) 3,000,000                                
Aurigene | Phase 1 clinical trial, dosing of fifth patient, IRAK4 program                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Waived payment of milestone and other payments (up to) 4,000,000                                
Number of patients dosed that trigger payment | patient                 5,000       5,000        
Aurigene | Extended exclusivity, PD1/VISTA program                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Waived payment of milestone and other payments (up to) 1,000,000                                
Aurigene | Phase 1 clinical trial, dosing of fifth patient, PD1/VISTA                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Waived payment of milestone and other payments (up to) 4,000,000                                
Number of patients dosed that trigger payment | patient                 5,000       5,000        
Aurigene | Option exercise payment, program three                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Waived payment of milestone and other payments (up to) $ 1,500,000                                
Percentage of consideration received 50.00%                                
Aurigene | Acceptance of IND filing, program three                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Waived payment of milestone and other payments (up to) $ 2,500,000                                
Aurigene | Program selection fee, program four                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Waived payment of milestone and other payments (up to) 2,000,000                                
Aurigene | Option exercise payment, program four                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Waived payment of milestone and other payments (up to) 3,000,000                                
Aurigene | Acceptance of IND filing, program four                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Waived payment of milestone and other payments (up to) $ 2,500,000                                
Aurigene | Maximum                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Collaboration agreement period                         5 years        
Percentage of contribution (up to)                 50.00%       50.00%        
Aurigene | Maximum | PD1/VISTA programs                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Collaboration agreement, payment per program (up to)                         $ 52,500,000        
Aurigene | Maximum | IRAK4 programs                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Collaboration agreement, payment per program (up to)                         52,500,000.0        
Aurigene | Maximum | Program three                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Collaboration agreement, payment per program (up to)                         50,000,000        
Aurigene | Maximum | Program four                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Collaboration agreement, payment per program (up to)                         50,000,000.0        
Aurigene | Maximum | Program thereafter                                  
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                  
Collaboration agreement, payment per program (up to)                         $ 140,500,000