X0201 4 2004-01-16 0 0001108205 CURIS INC CRIS 0001196573 MISSLING CHRISTOPHER U 61 MOULTON ST CAMBRIDGE MA 02138 0 1 0 0 Sr. VP, Strategic Planning Common Stock 2004-01-16 4 M 0 22850 0.68 A 0 D Common Stock 2004-01-20 4 M 0 11050 0.68 A 0 D Common Stock 2004-01-16 4 S 0 13350 6.25 D 0 D Common Stock 2004-01-16 4 S 0 3000 6.27 D 0 D Common Stock 2004-01-16 4 S 0 5600 6.28 D 0 D Common Stock 2004-01-16 4 S 0 900 6.29 D 0 D Common Stock 2004-01-20 4 S 0 3800 6.31 D 0 D Common Stock 2004-01-20 4 S 0 700 6.34 D 0 D Common Stock 2004-01-20 4 S 0 2150 6.35 D 0 D Common Stock 2004-01-20 4 S 0 1100 6.51 D 0 D Common Stock 2004-01-20 4 S 0 1800 6.5 D 0 D Common Stock 2004-01-20 4 S 0 1500 6.56 D 0 D Non-qualified stock option (right to buy) 0.68 2004-01-16 4 M 0 22850 0.68 D 2002-10-01 2012-06-05 Common Stock 22850 0 D Non-qualified stock option (right to buy) 0.68 2004-01-16 4 M 0 11050 0.68 D 2002-10-01 2012-06-05 Common Stock 11050 104600 D /s/ Michael P. Gray, Attorney-in-Fact 2004-01-21