Nature of Business (Details) - USD ($) $ in Thousands	3 Months Ended						9 Months Ended
	Sep. 30, 2022	Jun. 30, 2022	Mar. 31, 2022	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021	Sep. 30, 2022	Sep. 30, 2021	Nov. 09, 2022	Dec. 31, 2021
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Accumulated deficit	$ 1,137,667						$ 1,137,667			$ 1,092,325
Net loss	13,294	$ 15,940	$ 16,109	$ 11,051	$ 10,838	$ 9,927	45,343	$ 31,816
Cash used in operations							42,069	$ 29,448
Cash, cash equivalents, and investments	$ 98,700						$ 98,700
Subsequent Event
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Reduction in workforce (as a percent)									30.00%