Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 40,014	$ 129,610
Short-term investments	75,870	38,884
Accounts receivable	3,224	3,043
Prepaid expenses and other current assets	3,267	1,215
Total current assets	122,375	172,752
Long-term investments	23,964	14,564
Property and equipment, net	505	663
Restricted cash, long-term	726	816
Operating lease right-of-use asset	5,749	6,578
Goodwill	8,982	8,982
Other assets	0	3
Total assets	162,301	204,358
Current liabilities:
Accounts payable	6,417	4,166
Accrued liabilities	6,339	3,625
Current portion of operating lease liability	682	1,731
Current portion of long-term debt	0	557
Total current liabilities	13,438	10,079
Long-term operating lease liability	4,358	5,040
Liability related to the sale of future royalties, net	53,798	58,235
Long-term debt, net	0	334
Total liabilities	71,594	73,688
Commitments and contingencies
Stockholders’ equity (deficit):
Common stock, $0.01 par value—227,812,500 shares authorized, 91,645,369 shares issued and outstanding at December 31, 2021; 151,875,000 shares authorized, 91,502,461 shares issued and outstanding at December 31, 2020	916	915
Additional paid-in capital	1,182,225	1,176,647
Accumulated deficit	(1,092,325)	(1,046,889)
Accumulated other comprehensive loss	(109)	(3)
Total stockholders’ equity	90,707	130,670
Total liabilities and stockholders’ equity	$ 162,301	$ 204,358