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Liability Related to the Sale of Future Royalties (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 22, 2019
Mar. 31, 2020
Dec. 31, 2019
Mar. 31, 2019
Nonmonetary Transaction [Line Items]        
Proceeds from royalty interest purchase agreement with Oberland Capital Management, LLC   $ 0   $ 65,000
Payment towards debt obligations   0   $ 1,825
Transaction fees $ 600      
Non-cash interest rate (percent) 8.20%      
Carrying value of liability related to the sale of future royalties at January 1, 2020 $ 65,000   $ 62,477  
Amortization of capitalized issuance costs   15    
Capitalized issuance costs     (584)  
Imputed interest expense recognized for the three months ended March 31, 2020   1,283 4,055  
Less: payments to Oberland Capital, LLC   (2,786) (5,994)  
Carrying value of liability related to the sale of future royalties at March 31, 2020   $ 60,989 $ 62,477  
Oberland Capital        
Nonmonetary Transaction [Line Items]        
Proceeds from royalty interest purchase agreement with Oberland Capital Management, LLC 65,000      
Cash proceeds from royalty purchase agreement 70,700      
Purchaser default option period (days)   180 days    
HealthCare Royalty Partners III, L.P.        
Nonmonetary Transaction [Line Items]        
Proceeds from royalty interest purchase agreement with Oberland Capital Management, LLC 27,500      
Payment towards debt obligations 37,200      
Repayment of debt, principal 33,800      
Accrued and unpaid interest and prepayment fees 3,400      
Transaction fees 300      
Royalty Amounts in 2021 | Oberland Capital        
Nonmonetary Transaction [Line Items]        
Cash proceeds from royalty purchase agreement 17,200      
Royalty amount threshold 18,000      
Aggregate Net Royalties Prior to 2027 | Oberland Capital        
Nonmonetary Transaction [Line Items]        
Cash proceeds from royalty purchase agreement 53,500      
Royalty amount threshold $ 117,000