Commitments and Contingencies - Additional Information (Details) - USD ($)	3 Months Ended
	Mar. 31, 2026	Mar. 31, 2025	Dec. 31, 2025	Aug. 31, 2004
Accrued Payments
Collaboration revenue	$ 0	$ 2,000
Prepaid expenses and other current assets	616,000		$ 600,000
Other long-term assets	831,000		887,000
Accounts payable	400,000		$ 613,000
Periodic payment for agreement settlement	$ 285,000
Warrant exercise per share	$ 9.63		$ 9.63
Common stock, shares issued	2,378,383		2,349,480
Common stock, par value	$ 0.001		$ 0.001
The University of Texas MD Anderson Cancer Center and The Texas A & M University System [Member]
Accrued Payments
Milestone maximum payment				$ 4,500,000
Prepaid expenses and other current assets	$ 388,000
The University of Texas MD Anderson Cancer Center and The Texas A & M University System [Member] | Royalty [Member]
Accrued Payments
Payment under license agreement	0	0
The University of Texas MD Anderson Cancer Center [Member]
Accrued Payments
Accounts payable	57,000		$ 143,000
Collaboration Agreement with Solasia Pharma KK [Member]
Accrued Payments
Collaboration revenue	$ 0	$ 2,000