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Commitments and Contingencies - Additional Information (Details) - USD ($)						3 Months Ended		9 Months Ended
	Nov. 04, 2025	Jul. 03, 2025	Jul. 02, 2025	Jul. 01, 2025	Apr. 13, 2025	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024	Jun. 30, 2025	May 31, 2025	Mar. 31, 2025	Dec. 31, 2024	Aug. 31, 2004
Accrued Payments
Collaboration revenue						$ 0	$ 0	$ 2,000	$ 6,000
Prepaid expenses and other current assets						747,000		747,000					$ 1,659,000
Other long-term assets						942,000		942,000					0
Accounts payable						$ 843,000		$ 843,000					$ 516,000
Warrant exercise per share						$ 6.08		$ 6.08			$ 4		$ 28.5
Strategic and advisory services fee				$ 250,000
Common stock, shares issued						2,205,846		2,205,846					1,601,252
Common stock, par value						$ 0.001		$ 0.001					$ 0.001
Chief Executive Officer [Member]
Accrued Payments
Annual base salary			$ 275,000
Chief Executive Officer [Member] \| Stock Options [Member] \| Common Stock [Member]
Accrued Payments
Stock option to purchase shares			130,000
Stock option purchase of common stock exercise price			$ 5.06
Board of Directors [Member]
Accrued Payments
Deferred board service fee		$ 37,000			$ 139,000
Common stock, shares issued		7,450			38,269
R&D Agreement [Member] \| Subsequent Event [Member]
Accrued Payments
Contingency accrual, payments	$ 192,000
The University of Texas MD Anderson Cancer Center and The Texas A & M University System [Member]
Accrued Payments
Milestone maximum payment														$ 4,500,000
The University of Texas MD Anderson Cancer Center and The Texas A & M University System [Member] \| Royalty [Member]
Accrued Payments
Payment under license agreement								$ 0	0
The University of Texas MD Anderson Cancer Center [Member]
Accrued Payments
Accounts payable						$ 285,000		285,000		$ 285,000		$ 262,000	$ 257,000
Collaboration Agreement with Solasia Pharma KK [Member] \| Royalty [Member]
Accrued Payments
Collaboration revenue							$ 0	2,000	$ 6,000
M D Anderson License and The 2015 and 2019 Research and Development Agreement [Member]
Accrued Payments
Clinical expenses						$ 0		$ 28,000