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STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid In Capital
Accumulated Deficit
Balance at Dec. 31, 2018 $ 85,564 $ 161 $ 651,732 $ (566,329)
Balance (in shares) at Dec. 31, 2018   161,066,136    
Stock-based compensation 4,741   4,741  
Exercise of employee stock options 1,020   1,020  
Exercise of employee stock options (in shares)   352,652    
Restricted stock awards 1,000 $ 1 999  
Restricted stock awards (in shares)   1,408,536    
Issuance of common stock upon exercise of warrants, net 52,499 $ 18 52,481  
Issuance of common stock upon exercise of warrants, net (in shares)   17,803,031    
Issuance of inducement warrants 60,751   60,751  
Cancelled restricted common stock (in shares)   (74,599)    
Restricted stock buy-back at vesting to cover taxes (370)   (370)  
Restricted stock buy-back at vesting to cover taxes (in shares)   (165,178)    
Issuance of common stock in connection with at the market offering, net 2,971 $ 1 2,970  
Issuance of common stock in connection with at the market offering, net (in shares)   639,442    
Net loss (102,050)     (102,050)
Balance at Sep. 30, 2019 106,126 $ 181 774,324 (668,379)
Balance (in shares) at Sep. 30, 2019   181,030,020    
Balance at Jun. 30, 2019 61,995 $ 162 656,216 (594,383)
Balance (in shares) at Jun. 30, 2019   162,477,963    
Stock-based compensation 1,486   1,486  
Exercise of employee stock options 420   420  
Exercise of employee stock options (in shares)   94,584    
Restricted stock awards (in shares)   15,000    
Issuance of common stock upon exercise of warrants, net 52,499 $ 18 52,481  
Issuance of common stock upon exercise of warrants, net (in shares)   17,803,031    
Issuance of inducement warrants 60,751   60,751  
Issuance of common stock in connection with at the market offering, net 2,971 $ 1 2,970  
Issuance of common stock in connection with at the market offering, net (in shares)   639,442    
Net loss (73,996)     (73,996)
Balance at Sep. 30, 2019 106,126 $ 181 774,324 (668,379)
Balance (in shares) at Sep. 30, 2019   181,030,020    
Balance at Dec. 31, 2019 95,010 $ 182 778,953 (684,125)
Balance (in shares) at Dec. 31, 2019   181,803,320    
Stock-based compensation 5,393   5,393  
Exercise of employee stock options $ 43   43  
Exercise of employee stock options (in shares) 22,916 22,916    
Restricted stock awards   $ 1 (1)  
Restricted stock awards (in shares)   555,900    
Cancelled restricted common stock (in shares)   (141,230)    
Issuance of common stock in connection with a public offering, net $ 88,661 $ 29 88,632  
Issuance of common stock in connection with a public offering, net (in shares)   29,110,111    
Issuance of common stock in connection with at the market offering, net 13,015 $ 2 13,013  
Issuance of common stock in connection with at the market offering, net (in shares)   2,814,673    
Net loss (57,204)     (57,204)
Balance at Sep. 30, 2020 144,918 $ 214 886,033 (741,329)
Balance (in shares) at Sep. 30, 2020   214,165,690    
Balance at Jun. 30, 2020 163,414 $ 214 884,214 (721,014)
Balance (in shares) at Jun. 30, 2020   214,150,940    
Stock-based compensation 1,792   1,792  
Exercise of employee stock options 27   27  
Exercise of employee stock options (in shares)   14,750    
Net loss (20,315)     (20,315)
Balance at Sep. 30, 2020 $ 144,918 $ 214 $ 886,033 $ (741,329)
Balance (in shares) at Sep. 30, 2020   214,165,690