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Warrants - Additional Information (Detail) - USD ($)
3 Months Ended 9 Months Ended
Sep. 12, 2019
Nov. 11, 2018
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Fair Value Assumptions Expected volatility Rate Maximum     74.18% 78.34%    
Fair Value Assumptions Risk Free Interest Rate Maximum     0.39% 1.92%    
Fair Value Assumptions Expected Term1       6 years 3 months    
Fair Value Assumptions Expected Dividend Rate     0.00% 0.00%    
Net Proceeds from Underwriting       $ 2,971,000 $ 13,015,000 $ 2,971,000
Proceeds from private placement $ 52,500,000          
Non-cash inducement warrant expense       $ 60,751,000   $ 60,751,000
MD Anderson Warrant [Member]            
Number of securities into which the class of warrant converted     3,333,333   3,333,333  
Warrant Exercise Per share     $ 0.001   $ 0.001  
fair value of adjustment of warrants         $ 14,500,000  
Warrant Expiry date     Dec. 31, 2026   Dec. 31, 2026  
Securities Purchase Agreement [Member]            
Net Proceeds from Underwriting   $ 47.1     $ 47,100,000  
Private Placement [Member]            
Number of securities into which the class of warrant converted 17,803,031   18,939,394   18,939,394  
Warrant Exercise Per share $ 3.01   $ 3.01   $ 3.01  
fair value of adjustment of warrants         $ 18,400,000  
Fair Value Assumptions Expected volatility Rate Maximum         71.00%  
Fair Value Assumptions Risk Free Interest Rate Maximum         2.99%  
Fair Value Assumptions Expected Term1         5 years  
Fair Value Assumptions Expected Dividend Rate         0.00%  
Placement agent fees and other expenses $ 1,100,000          
Private Placement [Member] | New Warrants [Member]            
Number of securities into which the class of warrant converted 17,803,031          
Warrant Exercise Per share $ 7.00          
Non-cash inducement warrant expense         $ 60,800,000