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Warrants - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 6 Months Ended
Sep. 12, 2019
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Fair Value Assumptions Expected volatility Rate Maximum   73.90% 78.85%  
Fair Value Assumptions Risk Free Interest Rate Maximum   0.60% 2.42%  
Fair Value Assumptions Expected Dividend Rate   0.00% 0.00%  
Net Proceeds from Underwriting       $ 13,015
Proceeds from private placement $ 52,500      
MD Anderson Warrant [Member]        
Number of securities into which the class of warrant converted   3,333,333   3,333,333
Warrant Exercise Per share   $ 0.001   $ 0.001
fair value of adjustment of warrants       $ 14,500
Warrant Expiry date   Dec. 31, 2026   Dec. 31, 2026
Securities Purchase Agreement [Member]        
Net Proceeds from Underwriting       $ 47,100
Private Placement [Member]        
Number of securities into which the class of warrant converted 17,803,031 18,939,394   18,939,394
Warrant Exercise Per share $ 3.01 $ 3.01   $ 3.01
fair value of adjustment of warrants       $ 18,400
Fair Value Assumptions Expected volatility Rate Maximum       71.00%
Fair Value Assumptions Risk Free Interest Rate Maximum       2.99%
Fair Value Assumptions Expected Term1       5 years
Fair Value Assumptions Expected Dividend Rate       0.00%
Placement agent fees and other expenses $ 1,100      
Private Placement [Member] | New Warrants [Member]        
Number of securities into which the class of warrant converted 17,803,031      
Warrant Exercise Per share $ 7.00      
Non-cash inducement warrant expense       $ 60,800