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Stock Option Activity Under Stock Option Plan (Detail) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Number of Shares      
Beginning Balance 3,852,135 3,465,335 3,481,468
Granted 1,744,950 688,800 362,800
Exercised (104,167) (180,000) (234,833)
Cancelled (215,833) (122,000) (144,100)
Ending Balance 5,277,085 3,852,135 3,465,335
Options exercisable, at end of period 3,099,935 2,925,502  
Weighted Average Exercise Price      
Beginning Balance $ 5.12 $ 5.07 $ 4.96
Granted 2.35 5.27 6.40
Exercised 2.30 3.67 4.57
Cancelled 5.72 6.64 6.43
Ending Balance 4.24 5.12 $ 5.07
Options exercisable, at end of period $ 5.15 $ 5.12  
Options available for future grant 3,895,923    
Weighted Average Contractual Term (Years)      
Outstanding, at end of period 6 years 10 months 10 days    
Options exercisable, at end of period 4 years 11 months 5 days 5 years 6 months 29 days  
Aggregate Intrinsic Value      
Outstanding, at end of period $ 88    
Options exercisable, at end of period $ 88 $ 1,152