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Reconciliation of Income Tax Expense (Benefit) (Detail)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Income Tax Disclosure [Abstract]      
Federal income tax at statutory rates 34.00% 34.00% 34.00%
State income tax, net of federal tax benefit 4.00% 1.00% 5.00%
Research and development credits 3.00% 3.00% 3.00%
Stock compensation (1.00%) (1.00%) (1.00%)
Channel rights 0.00% (25.00%) 0.00%
Research and development true-up (7.00%) 0.00% 0.00%
Officers compensation (2.00%) 0.00% 0.00%
Other (3.00%) 0.00% 0.00%
Federal rate change (124.00%) 0.00% 0.00%
Increase in valuation allowance 96.00% (12.00%) (41.00%)
Effective tax rate 0.00% 0.00% 0.00%