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Fair Value of Stock Options Assumptions Using Black-Scholes Option Valuation Model (Detail)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]      
Risk-free interest rate, Minimum 1.85% 1.27% 1.46%
Risk-free interest rate, Maximum 2.27% 2.09% 1.93%
Expected life in years 6 years 6 years 6 years
Expected volatility, Minimum 80.31% 79.15% 79.13%
Expected volatility, Maximum 81.03% 82.95% 86.81%
Expected dividend yield 0.00% 0.00% 0.00%