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Selected Quarterly Information (Unaudited) (Tables)
12 Months Ended
Dec. 31, 2017
Quarterly Financial Information Disclosure [Abstract]  
Selected Quarterly Information
Year Ended December 31, 2017    First
Quarter
     Second
Quarter
     Third
Quarter
     Fourth
Quarter
 

Revenue

   $ 1,597      $ 1,597      $ 1,598      $ 1,597  

Total operating expenses

     15,562        14,611        14,676        15,033  

Loss from operations

     (13,965      (13,014      (13,078      (13,436

Preferred stock dividends

     (4,171      (4,865      (4,903      (4,999

Net (loss) applicable to common shareholders

     (19,658      (17,727      (17,604      (18,272

Loss per share, basic and diluted

   $ (0.15    $ (0.13    $ (0.13    $ (0.12
Year Ended December 31, 2016    First
Quarter
     Second
Quarter
     Third
Quarter
     Fourth
Quarter
 

Revenue

   $ 1,969      $ 1,697      $ 1,598      $ 1,597  

Total operating expenses

     14,009        132,939        12,512        12,708  

Loss from operations

     (12,040      (131,242      (10,914      (11,111

Preferred stock dividends

     —          —          (3,591      (3,532

Net (loss) applicable to common shareholders

     (12,019      (131,200      (14,445      (14,756

Loss per share, basic and diluted

   $ (0.09    $ (1.01    $ (0.11    $ (0.11