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STATEMENT OF STOCKHOLDERS' EQUITY (DEFICIT) - 6 months ended Jun. 30, 2016 - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-in Capital Common Stock
Accumulated Deficit
Beginning Balance (in shares) at Dec. 31, 2015   131,718,579    
Beginning Balance at Dec. 31, 2015 $ 87,371 $ 132 $ 579,939 $ (492,700)
Stock-based compensation $ 4,075   4,075  
Exercise of employee stock options (in shares) 169,000 137,346    
Exercise of employee stock options $ 551 $ 1 550  
Repurchase of common stock (in shares)   (168)    
Repurchase of common stock (2)   (2)  
Restricted stock buy-back at vesting to cover taxes (in shares)   (123,334)    
Restricted stock buy-back at vesting to cover taxes (853) $ (1) (852)  
Issuance of common stock in a license agreement 87   87  
Net loss (143,219)     (143,219)
Ending Balance (in shares) at Jun. 30, 2016   131,732,423    
Ending Balance at Jun. 30, 2016 $ (51,990) $ 132 $ 583,797 $ (635,919)