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Related Party Transactions - Additional Information (Detail) - USD ($)							1 Months Ended	3 Months Ended		9 Months Ended
	Sep. 28, 2015	Jun. 29, 2015	Mar. 27, 2015	Feb. 02, 2015	Jan. 13, 2015	Jan. 06, 2011	Jul. 31, 2015	Sep. 30, 2015	Sep. 30, 2014	Sep. 30, 2015	Sep. 30, 2014
Related Party Transaction [Line Items]
Commitment to purchase common stock										$ 34,000
Research and Development Expense								$ 16,970,000	$ 9,733,000	98,643,000	$ 24,621,000
Stock buy back										34,000
Minimum
Related Party Transaction [Line Items]
Research and Development Expense					$ 15,000,000
License Agreement
Related Party Transaction [Line Items]
Research and Development Expense										$ 67,300,000
Issuance of common stock in licensing agreement (in shares)										11,722,163
Md Anderson Cancer Center \| Minimum
Related Party Transaction [Line Items]
Ownership percentage								5.00%		5.00%
Intrexon Corporation
Related Party Transaction [Line Items]
Commitment to purchase common stock			$ 43,500,000			$ 50,000,000
Percentage of commitment for payments from receipts of upfronts, milestones and royalties			50.00%
Stock issued during period				1,440,000
Stock buy back (Shares)		3,711
Stock buy back		$ 34,000
Share buy back discount on closing price		5.00%
Amounts paid for services incurred										$ 11,700,000	9,100,000
Amount due to related party, current								$ 5,700,000	$ 2,300,000	$ 5,700,000	$ 2,300,000
Licensing fee	$ 10,000,000						$ 115,000,000