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Related Party Transactions - Additional Information (Detail) (USD $)
3 Months Ended 0 Months Ended
Mar. 31, 2015
Mar. 31, 2014
Feb. 02, 2015
Mar. 27, 2015
Dec. 31, 2014
Related Party Transaction [Line Items]          
Commitment to purchase common stock $ 246,000us-gaap_PaymentsForRepurchaseOfCommonStock $ 132,000us-gaap_PaymentsForRepurchaseOfCommonStock      
Accrued expenses 8,220,000us-gaap_AccruedLiabilitiesCurrent       7,182,000us-gaap_AccruedLiabilitiesCurrent
Md Anderson Cancer Center | Minimum          
Related Party Transaction [Line Items]          
Ownership percentage 5.00%us-gaap_EquityMethodInvestmentOwnershipPercentage
/ dei_LegalEntityAxis
= ziop_MdAndersonCancerCenterMember
/ us-gaap_RangeAxis
= us-gaap_MinimumMember
       
Intrexon Corporation          
Related Party Transaction [Line Items]          
Amounts paid for services incurred 3,000,000us-gaap_OperatingExpenses
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_IntrexonCorporationMember
1,700,000us-gaap_OperatingExpenses
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_IntrexonCorporationMember
     
Accrued expenses 3,000,000us-gaap_AccruedLiabilitiesCurrent
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_IntrexonCorporationMember
500,000us-gaap_AccruedLiabilitiesCurrent
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_IntrexonCorporationMember
     
Stock issued during period     1,440,000us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_IntrexonCorporationMember
   
Intrexon Corporation | Before Amendment          
Related Party Transaction [Line Items]          
Commitment to purchase common stock       50,000,000us-gaap_PaymentsForRepurchaseOfCommonStock
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_IntrexonCorporationMember
/ us-gaap_StatementScenarioAxis
= ziop_BeforeAmendmentMember
 
Intrexon Corporation | After Amendment          
Related Party Transaction [Line Items]          
Commitment to purchase common stock       $ 43,500,000us-gaap_PaymentsForRepurchaseOfCommonStock
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_IntrexonCorporationMember
/ us-gaap_StatementScenarioAxis
= ziop_AfterAmendmentMember
 
Percentage of commitment for payments from receipts of upfronts, milestones and royalties       50.00%ziop_PercentageOfCommitmentAmount
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_IntrexonCorporationMember
/ us-gaap_StatementScenarioAxis
= ziop_AfterAmendmentMember