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Summary of Significant Accounting Policies - Additional Information (Detail) (USD $)
12 Months Ended 0 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Jan. 13, 2015
Jan. 09, 2015
Summary Of Significant Accounting Policies [Line Items]          
Research and Development Expense $ 32,706,000us-gaap_ResearchAndDevelopmentExpense $ 42,852,000us-gaap_ResearchAndDevelopmentExpense $ 83,446,000us-gaap_ResearchAndDevelopmentExpense    
Stock based compensation expenses 4,743,000us-gaap_ShareBasedCompensation 3,507,000us-gaap_ShareBasedCompensation 4,880,000us-gaap_ShareBasedCompensation    
Weighted average fair value of stock option granted $ 3.58us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue $ 2.51us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue $ 3.06us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue    
Subsequent Event          
Summary Of Significant Accounting Policies [Line Items]          
Research and development arrangement Terms       In connection with such transfer, the terms of the License also require us and Intrexon to enter into a research and development agreement with MD Anderson pursuant to which the Company will provide funding for certain research and development activities of MD Anderson for a period of three years  
Research and Development Service Agreement Quarterly Payment       3,750,000ziop_ResearchAndDevelopmentServiceAgreementQuarterlyPayment
/ us-gaap_SubsequentEventTypeAxis
= us-gaap_SubsequentEventMember
 
Period of milestone payment       60 days  
Subsequent Event | Letter Agreement          
Summary Of Significant Accounting Policies [Line Items]          
Incentive shares issued period         60 days
Subsequent Event | Letter Agreement | Ziopharm          
Summary Of Significant Accounting Policies [Line Items]          
Cash consideration for license agreement         1,597,602us-gaap_StockIssuedDuringPeriodSharesIssuedForCash
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_ZiopharmMember
/ us-gaap_SubsequentEventTypeAxis
= us-gaap_SubsequentEventMember
/ ziop_TypeOfAgreementAxis
= ziop_LetterAgreementMember
Cash consideration for license agreement         7,500,000us-gaap_StockIssuedDuringPeriodValueIssuedForCash
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_ZiopharmMember
/ us-gaap_SubsequentEventTypeAxis
= us-gaap_SubsequentEventMember
/ ziop_TypeOfAgreementAxis
= ziop_LetterAgreementMember
Subsequent Event | Letter Agreement | Intrexon Corporation          
Summary Of Significant Accounting Policies [Line Items]          
Cash consideration for license agreement         7,500,000us-gaap_StockIssuedDuringPeriodValueIssuedForCash
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_IntrexonCorporationMember
/ us-gaap_SubsequentEventTypeAxis
= us-gaap_SubsequentEventMember
/ ziop_TypeOfAgreementAxis
= ziop_LetterAgreementMember
Subsequent Event | License Agreement | Md Anderson Cancer Center          
Summary Of Significant Accounting Policies [Line Items]          
Contingent consideration of common stock payable period       60 days  
Subsequent Event | License Agreement | Ziopharm          
Summary Of Significant Accounting Policies [Line Items]          
Cash consideration for license agreement       10,124,561us-gaap_StockIssuedDuringPeriodSharesIssuedForCash
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_ZiopharmMember
/ us-gaap_SubsequentEventTypeAxis
= us-gaap_SubsequentEventMember
/ ziop_TypeOfAgreementAxis
= ziop_LicenseAgreementMember
 
Cash consideration for license agreement       50,000,000us-gaap_StockIssuedDuringPeriodValueIssuedForCash
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_ZiopharmMember
/ us-gaap_SubsequentEventTypeAxis
= us-gaap_SubsequentEventMember
/ ziop_TypeOfAgreementAxis
= ziop_LicenseAgreementMember
 
Subsequent Event | License Agreement | Intrexon Corporation          
Summary Of Significant Accounting Policies [Line Items]          
Cash consideration for license agreement       50,000,000us-gaap_StockIssuedDuringPeriodValueIssuedForCash
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= ziop_IntrexonCorporationMember
/ us-gaap_SubsequentEventTypeAxis
= us-gaap_SubsequentEventMember
/ ziop_TypeOfAgreementAxis
= ziop_LicenseAgreementMember
 
Employee Stock Option          
Summary Of Significant Accounting Policies [Line Items]          
Stock based compensation expenses 3,700,000us-gaap_ShareBasedCompensation
/ us-gaap_AwardTypeAxis
= us-gaap_EmployeeStockOptionMember
2,300,000us-gaap_ShareBasedCompensation
/ us-gaap_AwardTypeAxis
= us-gaap_EmployeeStockOptionMember
3,100,000us-gaap_ShareBasedCompensation
/ us-gaap_AwardTypeAxis
= us-gaap_EmployeeStockOptionMember
   
Restricted Stock          
Summary Of Significant Accounting Policies [Line Items]          
Stock based compensation expenses 1,000,000us-gaap_ShareBasedCompensation
/ us-gaap_AwardTypeAxis
= us-gaap_RestrictedStockMember
1,200,000us-gaap_ShareBasedCompensation
/ us-gaap_AwardTypeAxis
= us-gaap_RestrictedStockMember
1,700,000us-gaap_ShareBasedCompensation
/ us-gaap_AwardTypeAxis
= us-gaap_RestrictedStockMember
   
Employee and Director Awards          
Summary Of Significant Accounting Policies [Line Items]          
Stock based compensation expenses 4,700,000us-gaap_ShareBasedCompensation
/ us-gaap_AwardTypeAxis
= ziop_EmployeeAndDirectorAwardsMember
3,500,000us-gaap_ShareBasedCompensation
/ us-gaap_AwardTypeAxis
= ziop_EmployeeAndDirectorAwardsMember
4,900,000us-gaap_ShareBasedCompensation
/ us-gaap_AwardTypeAxis
= ziop_EmployeeAndDirectorAwardsMember
   
Other Assets | Lease Obligations          
Summary Of Significant Accounting Policies [Line Items]          
Restricted cash 388,000us-gaap_RestrictedCashAndCashEquivalents
/ us-gaap_BalanceSheetLocationAxis
= us-gaap_OtherAssetsMember
/ ziop_LeaseAgreementsAxis
= ziop_LeaseObligationsMember
       
Other Noncurrent Assets | Line of Credit          
Summary Of Significant Accounting Policies [Line Items]          
Restricted cash 103,000us-gaap_RestrictedCashAndCashEquivalents
/ us-gaap_BalanceSheetLocationAxis
= us-gaap_OtherNoncurrentAssetsMember
/ us-gaap_CreditFacilityAxis
= us-gaap_LineOfCreditMember
       
Minimum          
Summary Of Significant Accounting Policies [Line Items]          
Property and equipment useful life 3 years        
Minimum | Subsequent Event          
Summary Of Significant Accounting Policies [Line Items]          
Research and Development Expense       15,000,000us-gaap_ResearchAndDevelopmentExpense
/ us-gaap_RangeAxis
= us-gaap_MinimumMember
/ us-gaap_SubsequentEventTypeAxis
= us-gaap_SubsequentEventMember
 
Maximum          
Summary Of Significant Accounting Policies [Line Items]          
Property and equipment useful life 5 years        
Maximum | Subsequent Event          
Summary Of Significant Accounting Policies [Line Items]          
Research and Development Expense       $ 20,000,000us-gaap_ResearchAndDevelopmentExpense
/ us-gaap_RangeAxis
= us-gaap_MaximumMember
/ us-gaap_SubsequentEventTypeAxis
= us-gaap_SubsequentEventMember