Selected Quarterly Information (Unaudited)

12 Months Ended

Dec. 31, 2014

Selected Quarterly Information (Unaudited)

14. Selected Quarterly Information (Unaudited)

        (in thousands, except per share amount)

Year Ended December 31, 2014	First Quarter			Second Quarter			Third Quarter			Fourth Quarter
Revenue	$	200		$	200		$	633		$	340
Total operating expenses		9,984			11,377			12,575			10,936
Loss from operations		(9,784	)		(11,177	)		(11,942	)		(10,596	)
Change in fair value of warrants		82			5,600			5,847			194
Net (loss)		(9,711	)		(5,576	)		(6,093	)		(10,401	)
Loss per share, basic and diluted	$	(0.10	)	$	(0.06	)	$	(0.06	)	$	(0.09	)

Year Ended December 31, 2013	First Quarter			Second Quarter			Third Quarter			Fourth Quarter
Revenue	$	200		$	200		$	200		$	200
Total operating expenses		23,783			18,496			9,315			6,919
Loss from operations		(23,583	)		(18,296	)		(9,115	)		(6,719	)
Change in fair value of warrants		10,788			(403	)		(7,407	)		(1,793	)
Net (loss)		(12,799	)		(18,692	)		(16,713	)		(8,903	)
Loss per share, basic and diluted	$	(0.15	)	$	(0.22	)	$	(0.20	)	$	(0.09	)