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Stock-Based Compensation Expense Included in Statements of Operations (Detail) (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2007
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation $ 3,507 $ 4,880 $ 2,759 $ 27 $ 120
Income tax benefit             
Net share based employee compensation expense 3,507 4,880 2,759    
Research and Development Expense
         
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation 792 1,917 890    
General and Administrative Expense
         
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation $ 2,715 $ 2,963 $ 1,869