Selected Quarterly Information (Unaudited) (Tables)

112 Months Ended

Dec. 31, 2012

Selected Quarterly Information

(in thousands, except per share amount)

Year Ended December 31, 2012	First Quarter			Second Quarter			Third Quarter			Fourth Quarter
Revenue	$	200		$	200		$	200		$	200
Total operating expenses		18,833			23,166			21,927			39,043
Loss from operations		(18,633	)		(22,966	)		(21,727	)		(38,843	)
Change in fair value of warrants		(5,811	)		(650	)		3,945			8,566
Net (loss)		(24,470	)		(23,613	)		(17,824	)		(30,225	)
Loss per share, basic and diluted	$	(0.32	)	$	(0.30	)	$	(0.23	)	$	(0.37	)

Year Ended December 31, 2011	First Quarter			Second Quarter			Third Quarter			Fourth Quarter
Revenue	$	67		$	200		$	200		$	200
Total operating expenses		27,993			13,048			14,409			16,617
Loss from operations		(27,926	)		(12,848	)		(14,209	)		(16,417	)
Change in fair value of warrants		(11,080	)		2,115			13,388			3,160
Net (loss)		(39,008	)		(10,724	)		(802	)		(13,244	)
Loss per share, basic and diluted	$	(0.65	)	$	(0.16	)	$	(0.01	)	$	(0.19	)