Commitments and Contingencies - Additional Information (Details) - USD ($)	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024	Dec. 31, 2024	Oct. 22, 2019	Aug. 24, 2004
Accrued Payments
Collaboration revenue	$ 2,000	$ 1,000
Prepaid expenses and other current assets	746,000		$ 1,659,000
Other long-term assets	$ 1,053,000		$ 0
Warrant exercise per share	$ 28.5		$ 28.5
MD Anderson Warrant [Member]
Accrued Payments
Number of warrants				22,222
Warrant exercise per share				$ 1.5
Warrant expiry date				Dec. 31, 2026
The University of Texas MD Anderson Cancer Center and The Texas A & M University System [Member]
Accrued Payments
Milestone maximum payment					$ 4,500,000
The University of Texas MD Anderson Cancer Center and The Texas A & M University System [Member] | Royalty [Member]
Accrued Payments
Payment under license agreement	$ 0	0
Collaboration Agreement with Solasia Pharma KK [Member]
Accrued Payments
Collaboration revenue	0	0
Collaboration Agreement with Solasia Pharma KK [Member] | Royalty [Member]
Accrued Payments
Collaboration revenue	2,000	$ 1,000
M D Anderson License and The 2015 and 2019 Research and Development Agreement [Member]
Accrued Payments
Clinical expenses	$ 0