Leases - Additional Information (Details)			12 Months Ended
	Nov. 15, 2023 USD ($)	Apr. 19, 2023	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Nov. 01, 2023 ft²	Aug. 31, 2023 USD ($)	Jun. 30, 2022 ft²	Apr. 30, 2022 USD ($) ft²
Lease termination date			Apr. 19, 2023
Sublease term amendment		Jul. 31, 2026
Termination costs			$ 200,000
Gain on lease termination			$ 0	$ 298,000
Operating Lease Area | ft²						14,037
Gain (Loss) On Modification Of Lease					$ 100,000
Sublease Area | ft²								4,772
Lease term, description		a term expiring on June 30, 2025 with an option to extend through July 31, 2026
Operating Lease, Payments	$ 100,000			400,000
Recognition in exchange of Operating Lease Liabilities				0
Leases other than short-term lease				0
MD Anderson [Member]
Gain on lease termination				100,000
Other Income Expense [Member]
Lease income				43,000
Boston, MA [Member]
Gain on lease termination				$ 200,000
Houston, TX [Member]
Operating Lease Area | ft²									3,228
Right-of-use assets							$ 19,000		$ 400,000
Houston, TX [Member] | Previously Reported [Member]
Operating Lease Area | ft²									18,111