Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($) $ in Thousands			12 Months Ended
	Jul. 17, 2024	Jan. 31, 2024	Dec. 31, 2024	Dec. 31, 2023
Summary Of Significant Accounting Policies [Line Items]
Stock based compensation expenses			$ 435	$ 2,800
Pre stock split shares authorized	34,666,667	520,000,000
Post Stock Split Shares Authorized	5,000,000	34,666,667
Stockholders equity reverse stock split	The Third Charter Amendment became effective on July 17, 2024.	The Charter Amendment became effective on January 31, 2024.
Fixed asset impairment charges				4,800
Asset Impairment Charges			0	4,803
Collaboration revenue			$ 10	5
Office and computer equipment [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment useful life			3 years
Software [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment useful life			3 years
Laboratory equipment [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment useful life			5 years
Asset Impairment Charges				1,000
Leasehold improvements [Member]
Summary Of Significant Accounting Policies [Line Items]
Asset Impairment Charges				3,800
Property and equipment estimated useful life, Description [Extensible Enumeration]			us-gaap:UsefulLifeTermOfLeaseMember
Employee Stock Option
Summary Of Significant Accounting Policies [Line Items]
Stock based compensation expenses			$ 400	2,500
Restricted Stock [Member]
Summary Of Significant Accounting Policies [Line Items]
Stock based compensation expenses			0	300
Stock Options and Restricted Stock [Member]
Summary Of Significant Accounting Policies [Line Items]
Stock based compensation expenses			$ 400	$ 2,800