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Commitments and Contingencies - Additional Information (Details) - USD ($)
3 Months Ended
Oct. 20, 2023
Aug. 14, 2023
Mar. 17, 2023
Aug. 17, 2015
Jan. 13, 2015
Mar. 31, 2024
Mar. 31, 2023
Apr. 03, 2023
Oct. 22, 2019
Oct. 05, 2018
Aug. 24, 2004
Accrued Payments                      
Research and development expense           $ 126,000 $ 6,504,000        
Royalty amount             0        
Maximum royalty amount                   $ 100,000,000  
Collaboration revenue           1,000 0        
Unspecified monetary damages     $ 3,200,000                
Loss contingency, name of plaintiff     KBI Biopharma                
Litigation expense $ 1,000,000                    
MD Anderson Warrant [Member]                      
Accrued Payments                      
Number of warrants                 222,222    
Warrant exercise per share                 $ 0.015    
Warrant expiry date                 Dec. 31, 2026    
MD Anderson Agreement and Worldwide License [Member]                      
Accrued Payments                      
License agreement commencing date         Jan. 13, 2015            
MD Anderson License and the Research and Development Agreement [Member]                      
Accrued Payments                      
Reimbursement of historical costs                 $ 20,000,000    
Quarterly expense incurred           0 200,000        
Aggregate potential benchmark payments                 36,500,000    
Payments due prior to the first marketing approval                 $ 3,000,000    
CRADA Agreement [Member]                      
Accrued Payments                      
Agreement termination date   Oct. 13, 2023                  
Annual expense incurred           0 300,000        
The University of Texas MD Anderson Cancer Center and The Texas A & M University System [Member]                      
Accrued Payments                      
Milestone maximum payment                     $ 4,500,000
The University of Texas MD Anderson Cancer Center and The Texas A & M University System [Member] | Royalty [Member]                      
Accrued Payments                      
Payment under license agreement           0 0        
License Agreement with the National Cancer Institute [Member]                      
Accrued Payments                      
License expense           0 300,000        
Collaboration Agreement with Solasia Pharma KK [Member]                      
Accrued Payments                      
Collaboration revenue           0 0        
Collaboration Agreement with Solasia Pharma KK [Member] | Royalty [Member]                      
Accrued Payments                      
Collaboration revenue           1,000 0        
M D Anderson License and the Two Thousand Fifteen Research and Development Agreement [Member]                      
Accrued Payments                      
Clinical expenses           $ 0 $ 0        
Intrexon Corporation [Member]                      
Accrued Payments                      
Annual license fee               $ 75,000   100,000  
Expected additional milestones payable                   52,500,000  
Intrexon Corporation [Member] | T-cell receptor [Member]                      
Accrued Payments                      
Maximum royalty amount                   $ 100,000,000  
Portion of income payable to related party                   20.00%  
Minimum [Member] | MD Anderson License and the Research and Development Agreement [Member]                      
Accrued Payments                      
Research and development expense       $ 15,000,000              
Maximum [Member] | MD Anderson License and the Research and Development Agreement [Member]                      
Accrued Payments                      
Research and development expense       $ 20,000,000