Income Taxes - Additional Information (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022
Income Taxes [Line Items]
Net operating loss carryforwards	$ 148,009	$ 171,070
Deferred tax assets operating loss carryforwards without expire date	363,200
Research and development credit carryforwards	39,838	40,116
Reduced credits carryforward	0
Uncertain Tax Positions Adjustment	0	$ 0
Increase (decrease) in deferred tax assets	(25,800)
Domestic Tax Authority [Member]
Income Taxes [Line Items]
Net operating loss carryforwards	$ 704,900
Net operating loss carryforwards, expiration date	2037
Federal and State [Member]
Income Taxes [Line Items]
Deferred tax assets operating loss carryforwards with expire date	$ 341,700
Net operating loss carryforwards, expiration date	2043
Federal and State [Member] | Research Tax Credit Carryforward
Income Taxes [Line Items]
Research and development credit carryforwards	$ 39,800
State and Local Jurisdiction [Member]
Income Taxes [Line Items]
Net operating loss carryforwards	497,900
Increase (decrease) in deferred tax assets	$ 0