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Income Taxes - Reconciliation of Income Tax Expense (Benefit) (Detail)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Income Tax Disclosure [Abstract]    
Federal income tax at statutory rates 21.00% 21.00%
State income tax, net of federal tax benefit 3.00% 3.00%
Research and development credits 2.00% 3.00%
Research and development true-up (2.00%) 0.00%
Stock-based compensation (1.00%) (1.00%)
Federal/state rate change (5.00%) (2.00%)
Change in valuation allowance (18.00%) (24.00%)
Effective tax rate 0.00% 0.00%