Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Summary Of Significant Accounting Policies [Line Items]
Stock based compensation expenses	$ 3,528	$ 10,774
Weighted average fair value of stock option granted	$ 0.77	$ 2.62
Asset Impairment Charges	$ 0	$ 740
Operating Lease Impairment Loss		600
Collaboration revenue	$ 2,922	398
Office and computer equipment [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment useful life	3 years
Software [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment useful life	3 years
Laboratory equipment [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment useful life	5 years
Leasehold improvements [Member]
Summary Of Significant Accounting Policies [Line Items]
Asset Impairment Charges		100
Estimated useful life	Life of the lease
Stock Options [Member]
Summary Of Significant Accounting Policies [Line Items]
Stock based compensation expenses	$ 3,000	7,400
Restricted Stock [Member]
Summary Of Significant Accounting Policies [Line Items]
Stock based compensation expenses	500	3,400
Stock Options and Restricted Stock [Member]
Summary Of Significant Accounting Policies [Line Items]
Stock based compensation expenses	$ 3,500	$ 10,800