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Stock-Based Compensation Expense Included in Statement of Operations (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock-based compensation $ 808 $ 2,371 $ 2,651 $ 9,857
Research and Development Expense        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock-based compensation 145 535 673 2,115
General and Administrative Expense        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock-based compensation $ 663 $ 1,836 $ 1,978 $ 7,742