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Stock-Based Compensation Expense Included in Statement of Operations (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock-based compensation $ 990 $ 5,290 $ 1,844 $ 7,486
Research and Development Expense        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock-based compensation 214 847 528 1,580
General and Administrative Expense        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock-based compensation $ 776 $ 4,443 $ 1,315 $ 5,906