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USD ($)

USD ($) / shares
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   &lt;div style="margin-top: 12pt; font-size: 1pt"&gt;&amp;#160;
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       &lt;td&gt;
       &lt;b&gt;&lt;font style="font-family: 'Times New Roman', Times"&gt;10.&amp;#160;&amp;#160;&lt;/font&gt;&lt;/b&gt;
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       &lt;b&gt;&lt;font style="font-family: 'Times New Roman', Times"&gt;STOCKHOLDERS&amp;#8217;
       EQUITY&lt;/font&gt;&lt;/b&gt;
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   &lt;div style="margin-top: 6pt; font-size: 1pt"&gt;&amp;#160;
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       &lt;b&gt;&lt;i&gt;&lt;font style="font-family: 'Times New Roman', Times"&gt;Preferred
       Stock&lt;/font&gt;&lt;/i&gt;&lt;/b&gt;
   &lt;/div&gt;
   &lt;div style="margin-top: 6pt; font-size: 1pt"&gt;&amp;#160;
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       We currently have 10,000,000&amp;#160;shares, $0.001&amp;#160;par value,
       of authorized preferred stock, of which 1,000,000&amp;#160;shares
       have been designated as Series&amp;#160;A Junior Participating
       Preferred Stock. No preferred stock was issued or outstanding as
       of December&amp;#160;31, 2010 and 2009.
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   &lt;div style="margin-top: 12pt; font-size: 1pt"&gt;&amp;#160;
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   &lt;div align="left" style="margin-left: 2%; margin-right: 0%; font-size: 10pt; font-family: Arial, Helvetica; color: #000000; background: transparent"&gt;
       &lt;b&gt;&lt;i&gt;&lt;font style="font-family: 'Times New Roman', Times"&gt;Common
       Stock&lt;/font&gt;&lt;/i&gt;&lt;/b&gt;
   &lt;/div&gt;
   &lt;div style="margin-top: 6pt; font-size: 1pt"&gt;&amp;#160;
   &lt;/div&gt;
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       At the 2009 Annual Meeting, our stockholders approved an
       amendment to the Company&amp;#8217;s Amended and Restated Certificate
       of Incorporation to increase the Company&amp;#8217;s authorized
       number of shares of Common Stock from 150,000,000&amp;#160;shares to
       250,000,000&amp;#160;shares.
   &lt;/div&gt;
   &lt;div style="margin-top: 12pt; font-size: 1pt"&gt;&amp;#160;
   &lt;/div&gt;
   &lt;div align="left" style="margin-left: 2%; margin-right: 0%; font-size: 10pt; font-family: Arial, Helvetica; color: #000000; background: transparent"&gt;
       &lt;b&gt;&lt;i&gt;&lt;font style="font-family: 'Times New Roman', Times"&gt;Equity
       Sales&lt;/font&gt;&lt;/i&gt;&lt;/b&gt;
   &lt;/div&gt;
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   &lt;/div&gt;
   &lt;div align="left" style="margin-left: 0%; margin-right: 0%; text-indent: 4%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: transparent"&gt;
       In December 2009, we received net proceeds of
       $409.5&amp;#160;million after deducting underwriting commissions and
       estimated offering expenses from our issuance of
       17,250,000&amp;#160;shares of common stock at the public offering
       price of $24.75 per share.
   &lt;/div&gt;
   &lt;div style="margin-top: 6pt; font-size: 1pt"&gt;&amp;#160;
   &lt;/div&gt;
   &lt;div align="left" style="margin-left: 0%; margin-right: 0%; text-indent: 4%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: transparent"&gt;
       In May 2009, we received net proceeds of $220.8&amp;#160;million
       after deducting underwriting commissions and estimated offering
       expenses from our issuance of 11,979,166&amp;#160;shares of common
       stock at the public offering price of $19.20 per share.
   &lt;/div&gt;
   &lt;div style="margin-top: 6pt; font-size: 1pt"&gt;&amp;#160;
   &lt;/div&gt;
   &lt;div align="left" style="margin-left: 0%; margin-right: 0%; text-indent: 4%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: transparent"&gt;
       In April 2008, we issued 8.0&amp;#160;million Shares of our common
       stock, and Warrants to purchase up to 8.0&amp;#160;million shares of
       common stock to an institutional Investor. We received net
       proceeds of $46.0&amp;#160;million from our issuance of the Shares
       and the Warrants to the Investor. The Investor purchased the
       Shares and Warrants for a negotiated price of $5.92 per share of
       common stock purchased. On the Exercise Date, we entered into
       the Amendment to the warrant agreement. Pursuant to the terms of
       the Amendment, the exercise price of the Warrants was amended
       from $20.00 to $8.92 per share, and the Investor concurrently
       exercised the Warrants for 8,000,000&amp;#160;shares of common
       stock, resulting in aggregate cash proceeds to the Company of
       $71.4&amp;#160;million.
   &lt;/div&gt;
   &lt;div style="margin-top: 6pt; font-size: 1pt"&gt;&amp;#160;
   &lt;/div&gt;
   &lt;div align="left" style="margin-left: 0%; margin-right: 0%; text-indent: 4%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: transparent"&gt;
       The Warrants were recorded at fair value at issuance and were
       adjusted to fair value at each reporting period until the
       Exercise Date. Any change in fair value between reporting
       periods was recorded as other income (expense). The Warrants
       continued to be reported as a liability until they were
       exercised, at which time the Warrants were adjusted to fair
       value and reclassified from liabilities to stockholders&amp;#8217;
       equity. The fair value of the Warrants was estimated using the
       BSM option pricing model. The fair value of the Warrants on the
       Exercise Date was $275.5&amp;#160;million, compared with
       $133.0&amp;#160;million at December&amp;#160;31, 2009. During the years
       ended December&amp;#160;31, 2010 and 2009, losses of
       $142.6&amp;#160;million and $118.8&amp;#160;million, respectively, were
       recognized from valuation of the warrant liability. During the
       year ended December&amp;#160;31, 2008, we recorded a gain of
       $371,000 from valuation of the warrant liability.
   &lt;/div&gt;
   &lt;div style="margin-top: 6pt; font-size: 1pt"&gt;&amp;#160;
   &lt;/div&gt;
   &lt;div align="left" style="margin-left: 0%; margin-right: 0%; text-indent: 4%; font-size: 10pt; font-family: 'Times New Roman', Times; color: #000000; background: transparent"&gt;
       On October&amp;#160;11, 2007, we entered into an equity line of
       credit arrangement with Azimuth Opportunity Ltd.
       (&amp;#8220;Azimuth&amp;#8221;) pursuant to a Common Stock Purchase
       Agreement, which we amended in October 2008 and February 2009.
       As amended, the Common Stock Purchase Agreement provided that,
       upon the terms and subject to the conditions set forth therein,
       Azimuth was committed to purchase up to $130.0&amp;#160;million of
       our common stock over the approximate
       &lt;font style="white-space: nowrap"&gt;36-month&lt;/font&gt;
       term of the Common Stock Purchase Agreement. Pursuant to a
       single draw down notice, on October&amp;#160;10, 2008, we sold
       3,610,760&amp;#160;shares of our common stock at a price of $5.80
       per share to Azimuth for net proceeds of approximately
       $19.8&amp;#160;million. The Common Stock Purchase Agreement expired
       in October 2010.
   &lt;/div&gt;
   &lt;/div&gt;
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Reference 2: http://www.xbrl.org/2003/role/presentationRef
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