X0508 4 2024-07-25 0001082554 UNITED THERAPEUTICS Corp UTHR 0001106578 ROTHBLATT MARTINE A C/O UNITED THERAPEUTICS CORPORATION 1000 SPRING STREET SILVER SPRING MD 20910 true true false false Chairperson & CEO 1 Common Stock 2024-07-25 4 M 0 3600 129.49 A 3730 D Common Stock 2024-07-25 4 S 0 130 333.9273 D 3600 D Common Stock 2024-07-25 4 S 0 589 335.8487 D 3011 D Common Stock 2024-07-25 4 S 0 776 336.7172 D 2235 D Common Stock 2024-07-25 4 S 0 214 337.785 D 2021 D Common Stock 2024-07-25 4 S 0 5 339.218 D 2016 D Common Stock 2024-07-25 4 S 0 297 339.7968 D 1719 D Common Stock 2024-07-25 4 S 0 531 340.3856 D 1188 D Common Stock 2024-07-25 4 S 0 724 341.5953 D 464 D Common Stock 2024-07-25 4 S 0 244 342.5343 D 220 D Common Stock 2024-07-25 4 S 0 90 343.7887 D 130 D Common Stock 2024-07-26 4 M 0 3600 129.49 A 3730 D Common Stock 2024-07-26 4 S 0 812 336.9522 D 2918 D Common Stock 2024-07-26 4 S 0 723 337.9064 D 2195 D Common Stock 2024-07-26 4 S 0 1115 339.2866 D 1080 D Common Stock 2024-07-26 4 S 0 950 339.784 D 130 D Common Stock 166 I By Spouse Common Stock 245909 I By Trust Common Stock 1742 I By Trust Common Stock 28170 I By Trust Common Stock 324518 I By Trust Common Stock 45596 I By Trust Stock Options 129.49 2024-07-25 4 M 0 3600 0 D 2014-12-31 2024-12-31 Common Stock 3600 75869 D Stock Options 129.49 2024-07-26 4 M 0 3600 0 D 2014-12-31 2024-12-31 Common Stock 3600 72269 D This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on August 4, 2023. This plan will continue until the earlier of: (a) exhaustion of a tranche of 723,869 stock options that expire December 31, 2024; or (b) August 31, 2024. This transaction was executed in multiple trades at prices ranging from $333.73 to $334.015. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $335.36 to $336.32. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $336.375 to $337.31. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $337.475 to $338.075. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $338.63 to $339.45. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $339.66 to $340.065. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $340.15 to $340.825. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $341.22 to $342.095. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $342.32 to $343.30. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $343.435 to $343.87. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $336.37 to $337.36. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $337.38 to $338.37. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $338.57 to $339.565. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $339.57 to $340.135. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Shares held in family trusts as to which the Reporting Person is sole trustee and sole beneficiary or co-trustee and settlor with power to revoke. Shares held in family trusts as to which the Reporting Person is sole trustee and members of the Reporting Person's immediate family are beneficiaries. Shares held in family trusts as to which the Reporting Person's spouse is sole trustee and sole beneficiary or co-trustee and settlor with power to revoke. Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries. Shares held in family trusts as to which the Reporting Person's spouse shares investment power and the Reporting Person and/or immediate family members are beneficiaries. /s/ John S. Hess, Jr. under Power of Attorney 2024-07-29