X0306 4 2019-01-09 0001082554 UNITED THERAPEUTICS Corp UTHR 0001106578 ROTHBLATT MARTINE A C/O UNITED THERAPEUTICS CORPORATION 1040 SPRING STREET SILVER SPRING MD 20910 1 1 Chairman & CEO Common Stock 2019-01-09 4 M 0 7054 52.65 A 7194 D Common Stock 2019-01-09 4 S 0 1500 112.8429 D 5694 D Common Stock 2019-01-09 4 S 0 5454 113.5729 D 240 D Common Stock 2019-01-09 4 S 0 100 114.30 D 140 D Common Stock 2019-01-10 4 M 0 7054 52.65 A 7194 D Common Stock 2019-01-10 4 S 0 900 111.99 D 6294 D Common Stock 2019-01-10 4 S 0 2800 113.4242 D 3494 D Common Stock 2019-01-10 4 S 0 3354 114.1492 D 140 D Common Stock 166 I By Spouse Common Stock 683489 I By Trusts Stock Options 52.65 2019-01-09 4 M 0 7054 0 D 2009-12-31 2019-12-31 Common Stock 7054 119920 D Stock Options 52.65 2019-01-10 4 M 0 7054 0 D 2009-12-31 2019-12-31 Common Stock 7054 112866 D This exercise of stock options and corresponding sale of shares was pursuant to a Rule 10b5-1 trading plan (the "plan") entered into by the reporting person. The plan is designed to exercise and sell up to 148,138 stock options (which expire at the end of 2019) during the month of January 2019, in equal tranches of approximately 7,055 shares per day assuming certain conditions are met. This transaction was executed in multiple trades at prices ranging from $112.24 to $113.18. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $113.24 to $114.22. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $111.50 to $112.45. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $112.94 to $113.92. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $113.99 to $114.43. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ John S. Hess, Jr. under Power of Attorney 2019-01-10