X0306 4 2015-04-15 0001082554 UNITED THERAPEUTICS Corp UTHR 0001106578 ROTHBLATT MARTINE A C/O UNITED THERAPEUTICS CORPORATION 1040 SPRING STREET SILVER SPRING MD 20910 1 1 Chairman & Co-CEO Common Stock 2015-04-15 4 M 0 2211 63.22 A 2451 D Common Stock 2015-04-15 4 S 0 300 184.6267 D 2151 D Common Stock 2015-04-15 4 S 0 1400 185.5204 D 751 D Common Stock 2015-04-15 4 S 0 511 186.76 D 240 D Common Stock 2015-04-16 4 M 0 4115 34.56 A 4355 D Common Stock 2015-04-16 4 S 0 4115 186.3921 D 240 D Common Stock 2015-04-16 4 M 0 5547 30.75 A 5787 D Common Stock 2015-04-16 4 S 0 700 186.2914 D 5087 D Common Stock 2015-04-16 4 S 0 1100 186.99 D 3987 D Common Stock 2015-04-16 4 S 0 2219 188.1967 D 1768 D Common Stock 2015-04-16 4 S 0 1228 189.0691 D 540 D Common Stock 2015-04-16 4 S 0 300 189.90 D 240 D Common Stock 166 I By Spouse Common Stock 579065.05 I By Trusts Stock Options 63.22 2015-04-15 4 M 0 2211 0 D 2010-12-31 2020-12-31 Common Stock 2211 428953 D Stock Options 34.56 2015-04-16 4 M 0 4115 0 D 2005-12-30 2015-12-30 Common Stock 4115 127580 D Stock Options 30.75 2015-04-16 4 M 0 5547 0 D 2009-12-26 2017-12-31 Common Stock 5547 493648 D This exercise of stock options and corresponding sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person. This transaction was executed in multiple trades at prices ranging from $183.99 to $184.97. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $185.08 to $186.00. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $186.41 to $187.035. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Exercise price and number of shares/awards has been adjusted to reflect the issuer's two-for-one stock split on September 22, 2009. This transaction was executed in multiple trades at prices ranging from $186.22 to $186.62. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $185.59 to $186.58. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $186.65 to $187.43. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $187.70 to $188.61. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $188.70 to $189.58. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $189.87 to $189.93. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ John S. Hess, Jr. under Power of Attorney 2015-04-16