X0306 4 2020-06-29 0 0001082554 UNITED THERAPEUTICS Corp UTHR 0001106578 ROTHBLATT MARTINE A C/O UNITED THERAPEUTICS CORPORATION 1040 SPRING STREET SILVER SPRING MD 20910 1 1 0 0 Chairman & CEO Common Stock 2020-06-29 4 M 0 10000 63.22 A 10140 D Common Stock 2020-06-29 4 S 0 3454 119.1299 D 6686 D Common Stock 2020-06-29 4 S 0 3759 120.035 D 2927 D Common Stock 2020-06-29 4 S 0 2356 120.9451 D 571 D Common Stock 2020-06-29 4 S 0 431 121.7398 D 140 D Common Stock 2020-06-30 4 M 0 10000 63.22 A 10140 D Common Stock 2020-06-30 4 S 0 6701 120.1617 D 3439 D Common Stock 2020-06-30 4 S 0 3299 120.7585 D 140 D Common Stock 166 I By Spouse Common Stock 663879 I By Trusts Stock Options 63.22 2020-06-29 4 M 0 10000 0 D 2010-12-31 2020-12-31 Common Stock 10000 64834 D Stock Options 63.22 2020-06-30 4 M 0 10000 0 D 2010-12-31 2020-12-31 Common Stock 10000 54834 D This exercise of options and sale of options is pursuant to a prearranged 10b5-1 trading plan. The trading plan contemplates the exercise and sale of up to 364,834 options with an exercise price of $63.22/share, which were granted in December 2010 and are set to expire at the end of 2020. Assuming relevant conditions are met, this tranche of options will be exercised in daily installments of 10,000 shares during May-July, 2020. This transaction was executed in multiple trades at prices ranging from $118.49 to $119.43. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $119.49 to $120.465. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $120.53 to $121.51. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $121.53 to $121.84. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $119.49 to $120.475. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $120.49 to $121.20. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ John S. Hess, Jr. under Power of Attorney 2020-07-01