Consolidated Balance Sheets (USD $) In Thousands, unless otherwise specified	Sep. 30, 2013	Dec. 31, 2012
Current assets:
Cash and cash equivalents	$ 128,025	$ 90,782
Certificate of deposit		2,153
Prepaid expenses and other current assets	1,720	643
Total current assets	129,745	93,578
In-process research and development	58,200	58,200
Other assets	101	117
Fixed assets, net	1,904	1,666
Total assets	189,950	153,561
Current liabilities:
Accounts payable	4,661	7,060
Accrued expenses	5,652	2,933
Accrued compensation	1,953	2,207
Accrued lease expense, current	303	295
Deferred rent	134	149
Capital lease obligations, current	64	96
Current portion of long term debt	7,055	3,007
Total current liabilities	19,822	15,747
Accrued lease expense, long-term	449	647
Capital lease obligations, long-term	16	64
Debt, long-term	12,538	16,221
Total liabilities	32,825	32,679
Shareholders' equity:
Common stock, $0.01 par value; 500,000,000 authorized shares, 39,100,899 and 31,488,204 issued and outstanding shares at September 30, 2013 and December 31, 2012, respectively	391	315
Additional paid-in capital	532,141	455,325
Warrant to purchase common stock		790
Accumulated deficit	(375,407)	(335,548)
Total shareholders' equity	157,125	120,882
Total liabilities and shareholders' equity	$ 189,950	$ 153,561