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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Income Statement [Abstract]      
Revenues $ 0 $ 240,000 $ 0
Costs and Expenses      
Operating expenses 2,915,369 3,284,666 11,884,775
Research and development expenses 577,501 893,452 2,011,486
Loss before other income (expense) (3,492,870) (3,938,118) (13,896,261)
Other income (expense)      
Other income (loss) 11,258 (28,598) (23,549)
Interest and financing expense (747,342) (39,619) (260)
Change in fair value of derivative liabilities 0 0 (220,614)
Gain on extinguishment of derivative liabilities 0 0 3,441,752
Gain on disposition of equipment 0 0 41,923
Net loss $ (4,228,954) $ (4,006,335) $ (10,657,009)
Net loss per common share, basic and diluted $ (.02) $ (0.02) $ (0.07)
Weighted average common shares outstanding, basic and diluted 182,267,719 180,386,712 160,958,284