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Consolidated Statements of Stockholders' Equity (USD $)
Total
Common Stock
Additional Paid-in Capital
Retained Deficit
Treasury Stock
Balance at Dec. 31, 2009 $ 40,077,441 $ 1,716,416 $ 245,029,557 $ (205,955,693) $ (712,839)
Balance (in shares) at Dec. 31, 2009   17,164,162.2     42,169
Increase (Decrease) in Stockholders' Equity          
Issuance of officer restricted stock units   371 (371)    
Issuance of officer restricted stock units (in shares)   3,705.2      
Shares issued through ESPP 122,668 4,364 118,304    
Shares issued through ESPP (in shares)   43,637.2      
Stock-based compensation 858,467   858,467    
Warrants issued to service provider 15,739   15,739    
Redeemable preferred stock converted to common stock 703,061 30,158 672,903    
Redeemable preferred stock converted to common stock (in shares)   301,577.7      
Redeemable preferred stock redeemed for common stock 1,317,522 59,887 1,257,635    
Redeemable preferred stock redeemed for common stock (in shares)   598,874.1      
Stock issued for dividends on redeemable preferred stock 78,826 3,582 75,244    
Stock issued for dividends on redeemable preferred stock (in shares)   35,821.9      
Issuance of stock for cash, net of issuance costs 2,237,764 99,296 2,138,468    
Issuance of stock for cash, net of issuance costs (in shares)   992,963.0      
Warrant exercises 5,902,038 182,679 5,719,359    
Warrant exercises (in shares)   1,826,787.5      
Rounding for fractional shares (in shares)   0.2      
Adjust par value for reverse stock split   (1,887,078) 1,887,078    
Net loss (22,679,766)     (22,679,766)  
Balance at Dec. 31, 2010 28,633,760 209,675 257,772,383 (228,635,459) (712,839)
Balance (in shares) at Dec. 31, 2010   20,967,529.0     42,169
Increase (Decrease) in Stockholders' Equity          
Issuance of officer restricted stock units   27 (27)    
Issuance of officer restricted stock units (in shares)   2,633.0      
Shares issued through ESPP 43,244 301 42,943    
Shares issued through ESPP (in shares)   30,104.0      
Stock-based compensation 724,249   724,249    
Redeemable preferred stock converted to common stock 10,611,809 41,409 10,570,400    
Redeemable preferred stock converted to common stock (in shares)   4,140,843.8      
Redeemable preferred stock redeemed for common stock 4,419,415 20,200 4,399,215    
Redeemable preferred stock redeemed for common stock (in shares)   2,020,022.2      
Stock issued for dividends on redeemable preferred stock 122,233 608 121,625    
Stock issued for dividends on redeemable preferred stock (in shares)   60,699.5      
Issuance of stock for cash, net of issuance costs (21,729)   (21,729)    
Warrant exercises 1,497,556 8,853 1,488,703    
Warrant exercises (in shares)   885,486.6      
Rounding for fractional shares (in shares)   (0.1)      
Net loss (17,018,451)     (17,018,451)  
Balance at Jun. 30, 2011 $ 29,012,086 $ 281,073 $ 275,097,762 $ (245,653,910) $ (712,839)
Balance (in shares) at Jun. 30, 2011   28,107,318.0     42,169