X0303 4 2009-06-24 0001103021 BIODELIVERY SCIENCES INTERNATIONAL INC BDSI 0001365385 CDC IV LLC 47 HULFISH STREET, SUITE 310 PRINCETON NJ 08542 0 0 1 0 0001365759 CDC Operations LLC 47 HULFISH STREET, SUITE 310 PRINCETON NJ 08542 0 0 1 0 0001352876 Ramsay David Russ 47 HULFISH STREET, SUITE 310 PRINCETON NJ 08542 0 0 1 0 0001204568 LESCHLY JAN 47 HULFISH STREET, SUITE 310 PRINCETON NJ 08542 0 0 1 0 0001191229 KARABELAS ARGERIS N 47 HULFISH STREET, SUITE 310 PRINCETON NJ 08542 0 0 1 0 Common Stock 2009-06-24 4 S 0 12559 6.4832 D 1063979 I See Footnote Common Stock 2009-06-25 4 S 0 38965 6.5058 D 1025014 I See Footnote On June 24, 2009, CDC IV, LLC sold an aggregate of 12,559 shares of Common Stock of BioDelivery Sciences International, Inc. at an average gross price per share of $6.4832. The individual trades made by CDC IV, LLC on June 24, 2009 are set forth on Exhibit 1(a) attached hereto. The reportable securities are owned directly by CDC IV, LLC and indirectly by CDC Operations LLC, David R. Ramsay, Argeris Karabelas and Jan Leschly. CDC Operations LLC disclaims beneficial ownership of the reportable securities and this report shall not be deemed an admission that CDC Operations LLC is the beneficial owner of such securities for purposes of Section 16 or any other purpose, except to the extent of its pecuniary interest therein. David R. Ramsay, Argeris Karabelas and Jan Leschly are each partners of CDC Operations LLC. Messrs. Ramsay, Karabelas and Leschly each disclaims beneficial ownership of the reportable securities and this report shall not be deemed an admission that Messrs. Ramsay, Karabelas and Leschly is the beneficial owner of such securities for purposes of Section 16 or any other purpose, except to the extent of their pecuniary interest therein. On June 25, 2009, CDC IV, LLC sold an aggregate of 38,965 shares of Common Stock of BioDelivery Sciences International, Inc. at an average gross price per share of $6.5058. The individual trades made by CDC IV, LLC on June 25, 2009 are set forth on Exhibit 1(b) attached hereto. /s/ David R. Ramsay 2009-06-26