Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2019	Mar. 31, 2018
Operating activities:
Net loss	$ (3,833)	$ (10,709)
Adjustments to reconcile net loss to net cash flows from operating activities
Depreciation	85	230
Accretion of debt discount and loan costs	634	625
Amortization of intangible assets	1,289	1,289
Provision (benefit) for inventory obsolescence	149	(66)
Stock-based compensation expense	1,141	2,921
Changes in assets and liabilities, net of effect of acquisition:
Accounts receivable	(2,381)	864
Inventories	(2,002)	716
Prepaid expenses and other assets	218	782
Accounts payable and accrued expenses	1,814	(3,413)
Net cash flows from operating activities	(2,886)	(6,761)
Investing activities:
BELBUCA acquisition		(1,951)
Purchase of equipment		(73)
Disposal of property and equipment	(79)
Net cash flows from investing activities	(79)	(2,024)
Financing activities:
Proceeds from exercise of stock options	472	130
Payment of deferred financing fees		(450)
Net cash flows from (used in) financing activities	472	(320)
Net change in cash and cash equivalents	(2,493)	(9,105)
Cash and cash equivalents at beginning of period	43,822	21,195
Cash and cash equivalents at end of period	41,329	12,090
Cash paid for interest	$ 1,931	$ 1,880