Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015
Operating activities:
Net income (loss)	$ 5,285	$ (67,138)	$ (37,672)
Adjustments to reconcile net income (loss) to net cash flows from operating activities
Depreciation	693	437	329
Accretion of debt discount and loan costs	2,392	397	500
Amortization of intangible assets	5,425	971	970
Provision for inventory obsolescence	243	0
Stock-based compensation expense	14,801	14,931	14,249
Deferred income taxes	(15,972)
Bargain purchase gain	(27,336)
Changes in assets and liabilities:
Accounts receivable	(5,884)	(862)	670
Inventories	2,448	(810)	(730)
Prepaid expenses and other assets	526	(203)	(1,365)
Accounts payable and accrued expenses	6,644	(1,546)	5,055
Deferred revenue	(21,716)	(159)	14,262
Net cash flows used in operating activities	(32,451)	(53,982)	(3,732)
Investing activities:
BELBUCA® acquisition	(5,853)
Purchase of equipment	(11)	(405)	(701)
Net cash flows used in investing activities	(5,864)	(405)	(701)
Financing activities:
Proceeds from sales of securities, net of costs incurred		40	(40)
Proceeds from exercise of stock options	439	297	755
Issuance of common stock		2,460
Issuance of warrants		49
Proceeds from exercise of common stock warrants			1
Payment on note payable	(30,000)		(3,335)
Proceeds from notes payable	60,000		20,667
Return of short swing profits			6
Payment of deferred financing fees	(2,948)		(533)
Net cash flows from financing activities	27,491	2,846	17,521
Net change in cash and cash equivalents	(10,824)	(51,541)	13,088
Cash and cash equivalents at beginning of year	32,019	83,560	70,472
Cash and cash equivalents at end of year	21,195	32,019	83,560
Cash paid for interest	5,285	$ 2,870	$ 1,885
Non-cash Operating, Financing and Investing Activities:
Fair value of bargain purchase price of BELBUCA acquisition	27,300
Fair value of warrants, in connection with CRG term loan	$ 6,000
Series A Preferred Stock [Member]
Non-cash Operating, Financing and Investing Activities:
Series A Preferred stock converted			45,845