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Note Payable (MidCap Loan) - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Millions
9 Months Ended
Feb. 21, 2017
Sep. 30, 2017
May 29, 2015
CRG [Member]      
Debt Instrument [Line Items]      
License termination effective date   Feb. 21, 2017  
Number of warrants to purchase common stock 1,701,583    
Exercise price of warrants to purchase common stock $ 2.38    
Secured Loan Facility [Member] | MidCap Financial Trust [Member]      
Debt Instrument [Line Items]      
Secured loan facility     $ 30.0
Net proceeds in aggregate amount $ 29.4    
Number of warrants to purchase common stock   84,986  
Exercise price of warrants to purchase common stock   $ 3.53  
Class Of Warrant Or Rights Date From Which Warrants Or Rights Expired   2021-05  
Interest Expense [Member] | MidCap Financial Trust [Member]      
Debt Instrument [Line Items]      
Deferred loan costs expensed   $ 0.7