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Business Combination and BELBUCA Acquisition - Summary of Proforma Impact of Acquisition (Detail) - BELBUCA [Member]
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2016
USD ($)
$ / shares
Business Acquisition [Line Items]  
Revenue | $ $ 25,010
Net loss | $ $ (201,769)
Pro forma net loss per common share  
Basic | $ / shares $ (3.76)
Diluted | $ / shares $ (3.76)