Condensed Consolidated Statements of Operations (Unaudited) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Revenues:
Product sales	$ 2,009	$ 1,155	$ 6,221	$ 2,665
Product royalty revenues	1,065	25	2,393	689
Research and development reimbursements	497	55	501	909
Contract revenues			2,500	11,759
Total Revenues:	3,571	1,235	11,615	16,022
Cost of sales	2,314	1,699	8,958	5,443
Expenses:
Research and development	4,402	4,473	13,786	15,527
General and administrative	12,054	14,715	37,606	41,185
Total Expenses:	16,456	19,188	51,392	56,712
Loss from operations	(15,199)	(19,652)	(48,735)	(46,133)
Interest expense, net	(786)	(785)	(2,477)	(1,732)
Derivative gain	14		36
Other (expense) income, net	(6)	(2)	(20)	21
Net loss	$ (15,977)	$ (20,439)	$ (51,196)	$ (47,844)
Basic and diluted loss per share:	$ (0.30)	$ (0.39)	$ (0.96)	$ (0.92)
Weighted average common stock shares outstanding, basic and diluted:	53,767,099	52,542,715	53,531,770	52,286,757