Condensed Consolidated Statements of Operations (Unaudited) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Revenues:
Product sales	$ 2,110	$ 833	$ 4,212	$ 1,510
Product royalty revenues	394	469	1,328	663
Research and development reimbursements		80	4	855
Contract revenues	2,500	351	2,500	11,759
Total Revenues:	5,004	1,733	8,044	14,787
Cost of sales	4,094	2,621	6,644	3,745
Expenses:
Research and development	4,008	4,506	9,385	11,054
Selling, general and administrative	12,496	13,287	25,551	26,468
Total Expenses:	16,504	17,793	34,936	37,522
Loss from operations	(15,594)	(18,681)	(33,536)	(26,480)
Interest expense, net	(914)	(527)	(1,691)	(947)
Derivative gain	22		22
Other (expense) income, net		(3)	(14)	23
Net loss	$ (16,486)	$ (19,211)	$ (35,219)	$ (27,404)
Basic and diluted loss per share:	$ (0.31)	$ (0.37)	$ (0.66)	$ (0.53)
Weighted average common stock shares outstanding:	53,594,979	52,401,747	53,412,813	52,156,657