Condensed Consolidated Statements of Operations (Unaudited) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2015	Sep. 30, 2014	Sep. 30, 2015	Sep. 30, 2014
Revenues:
Product sales	$ 1,155		$ 2,665
Product royalty revenues	25	$ 12	689	$ 1,858
Research and development reimbursements	55	1,298	909	12,067
Contract revenues		513	11,759	22,472
Total Revenues:	1,235	1,823	16,022	36,397
Cost of sales	1,699	463	5,443	1,875
Expenses:
Research and development	4,473	6,770	15,527	29,376
General and administrative	14,715	13,648	41,185	25,533
Total Expenses:	19,188	20,418	56,712	54,909
Loss from operations	(19,652)	(19,058)	(46,133)	(20,387)
Interest expense, net	(785)	(515)	(1,732)	(1,589)
Derivative loss		(5,685)		(14,631)
Other (expense) income, net	(2)	2	21	35
Net loss	$ (20,439)	$ (25,256)	$ (47,844)	$ (36,572)
Basic and diluted loss per share:	$ (0.39)	$ (0.51)	$ (0.92)	$ (0.77)
Weighted average common stock shares outstanding:	52,542,715	49,555,815	52,286,757	47,391,040