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Derivative Financial Instruments - Reconciliation of Beginning and Ending Balances of Assets and Liabilities Measured at Fair Value Using Significant Observable Inputs (Detail) (Midcap warrant [Member], Level 2 [Member], USD $)
6 Months Ended
Jun. 30, 2014
Midcap warrant [Member] | Level 2 [Member]
 
Fair Value Measurement Inputs Disclosure [Line Items]  
Warrant liability, Beginning balance $ 4,315,183
Decrease due to exercise of warrants (2,499,273)
Increase in fair value of warrants 8,945,782
Warrant liability, Ending balance $ 10,761,692
Warrant liability, Beginning balance, Number of warrants 1,999,436
Decrease due to exercise of warrants, Number of warrants (798,871)
Increase in fair value of warrants, number of warrants   
Warrant liability, Ending balance, Number of warrants 1,200,565