Consolidated Statements of Cash Flows (USD $)	12 Months Ended
	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2011
Operating activities:
Net (loss) income	$ (57,393,613)	$ 1,652,181	$ (23,325,116)
Adjustments to reconcile net (loss) income to net cash flows from operating activities
Depreciation	207,441	465,929	444,527
Accretion of debt discount	164,391
Amortization of intangible assets	1,139,832	1,020,878	890,980
Derivative (gain) loss	(121,228)	5,594,152	(3,463,453)
Stock-based compensation expense	3,327,014	1,619,269	1,226,724
Purchase of Arcion license with common stock	2,072,136
Changes in assets and liabilities:
Accounts receivable	(2,273,228)	(419,680)	530,544
Prepaid expenses and other assets	(68,928)	3,822	6,226
Accounts payable and accrued expenses	(656,795)	5,567,962	407,441
Income taxes payable		129,120
Deferred revenue	(6,499,838)	(3,446,309)	7,133
Net cash flows from operating activities	(60,102,816)	12,187,324	(23,274,994)
Investing activities:
Purchase of equipment	(76,893)	(38,550)	(286,973)
Purchase of intangible assets		(1,050,000)
Net cash flows from investing activities	(76,893)	(1,088,550)	(286,973)
Financing activities:
Proceeds from sales of securities		38,373,014	13,996,773
Proceeds from exercise of stock options	357,281	2,054,100	349,676
Proceeds from exercise of common stock warrants	50,000	921,019	1,749,259
Proceeds from notes payable and warrants	20,000,000
Payment of deferred financing fees	(241,070)
(Repayment of) proceeds from related party advances, net		(7,805)	7,805
Net cash flows from financing activities	20,166,211	41,340,328	16,103,513
Net change in cash and cash equivalents	(40,013,498)	52,439,102	(7,458,454)
Cash and cash equivalents at beginning of year	63,189,307	10,750,205	18,208,659
Cash and cash equivalents at end of year	23,175,809	63,189,307	10,750,205
Cash paid for interest	742,097
Cash paid for taxes	$ 80,457